Biomaterials and therapeutics laboratory

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The Suggs Lab aims to develop clinically relevant and robust strategies for enhancing the growth of cardiac and vascular tissue in vivo to restore function after injuries such as myocardial infarction, ischemia, and deep burns. Toward this goal we study the in vitro response of stem cells to pro-angiogenic gel materials we have developed, explore new strategies to encourage stem cell differentiation to cardiomyocytes, and assess the vessel forming ability of stem cells implanted within gel scaffolds in mouse injury models. We are also interested in creating novel self-assembling gel matrix materials for promoting angiogenesis that are injectable, biocompatible, and readily degradable into natural components that are easily metabolized by the body.


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2018 BMES Annual Meeting:

Derek Hernandez ("Real-time Sensors for Non-invasive Monitoring of Cell Therapies"), Kabir Dhada ("Imaging Stem Cell Viability using Photoacoustic Imaging"), and Jessica Widman ("Exploring the Cross-Talk Between Macrophages and Tumor Cells") will be giving talks and Shane Allen ("Dynamic ECM Stiffening Results in EMT and Migratory Transformation in Epithelial Cells"), Kiheon Baek ("Self-assembling nucleo-peptides as a platform for biologically active hydrogels") and Chelsea Kraynak ("Cell Membrane-Coated PLGA Nanoparticle to Modulate Inflammatory Macrophage Phenotype") will have posters.